Lana Pine

In patients with fibromyalgia, vitamin D supplementation improved physical function, and role limitations due to emotional health, general health, and social function.

The April 2023 rheumatology month in review highlights recent data regarding physical activity levels among patients with JIA, a link between fibromyalgia and psychiatric disorders, and a feature focused on the treatment of polymyalgia rheumatica.

GPX3, an antioxidant enzyme and reactive oxygen species scavenger, was categorized as a hub gene in rheumatoid arthritis neutrophils.

Compared with those without SLE, those with SLE had a higher risk of fetal morbidity and mothers were almost 4 times as likely to require a blood transfusion or develop a cerebrovascular disorder.

While age and fat mass were inversely associated with cardiorespiratory fitness (CRF), the physical activity index was positively associated with CRF.

Patients with fibromyalgia receiving the synbiotic intervention reported decreased levels of anxiety, depression, and stress, as well as improvements in quality of life during daily activities.

Women with rheumatoid arthritis (RA) in remission exhibited higher values of Disease Activity Score-28 for Rheumatoid Arthritis with erythrocyte sedimentation rate (DAS28-ESR) compared with men.

Between 2011 and 2018, age- and sex-adjusted prevalence among Asian Americans doubled from 3.3% to 6.6%, which exceeded all other ethnic and racial groups.

At month 6, 71.0% in the smart system of disease management group achieved a DAS28-CRP of 3.2 or less compared with 64.5% in the control group.

A negative relationship between bone mineral density (BMD) and hyperuricemia in total, as well as in the L1, L2, and L3 lumbar vertebrae, was demonstrated in the multivariable-adjusted regression models.

Patients with intercritical gout had higher CXCL12 levels, IL-18, and IL-1β when compared with controls.

Despite the recent advancements in the treatment of polymyalgia rheumatica, a need for more research focused on finding non-steroidal treatment options remains.

Although women with gout reported more severe symptoms and significantly worse illness perception and quality of life, they were given less information on ways to self-manage their condition.

Results revealed 92.45% of patients with fibromyalgia were simultaneously diagnosed with at least 1 type of psychiatric disorder, although most were diagnosed with 2 or more.

No significant changes in the rate of flares during the 6-month period pre- or post-vaccination were observed in patients with either rheumatoid arthritis or psoriatic arthritis.

No significant differences in the risk of myocardial infarction and other cardiovascular events were observed between patients with gout who received colchicine and those who did not.

Patients with cirrhosis had higher mortality rates, tophi, and gout flare.

Results of a recent study found that fibromyalgia may be more common among individuals with opioid use disorder, and that treating fibromyalgia may be beneficial for treating opioid use disorder.

Patients with fibromyalgia were more likely to report that pain caused them to continue using opioids, to increase the amount of opioids they used over time, and to delay getting addiction treatment.

The meta-analysis observed an enhanced plasma uric acid concentration in patients with periodontitis when compared with controls.

At month 3, patients treated with tofacitinib achieved higher rates of ACR20/50, MDA, and PASI75 in both sexes when compared with the placebo. However, female patients were less likely to achieve MDA when compared with males.

At week 24, serum IGF-1 levels increased and body weight was reduced by an average of 6.5% from baseline.

In a multivariate logistic regression analysis, the HAQ score was significantly associated with both anxiety and depression, indicating worse functional status and higher disease activity.

Soumya Chakravarty, MD, PhD, discussed the results of the DISCOVER-1 and DISCOVER-2 studies that evaluated the long-term efficacy of guselkumab for the treatment of adult patients with active psoriatic arthritis.

The collaboration, titled the Lupus Accelerating Breakthroughs Consortium (Lupus ABC), is the first public-private partnership designed to advance lupus discoveries and highlight patient perspective in drug development.

A cross-sectional, case-controlled cohort study evaluated the cardiorespiratory and neuromuscular fitness of Finnish patients with JIA and healthy controls.

Treatment with secukinumab was safe and effective for patients with ankylosing spondylitis and psoriatic arthritis, with significant reductions in disease activity scores observed through 52 weeks.

Although the ultimate results of the study were unsurprising to Shai Efrati, MD, PhD, the magnitude of improvement was much higher than he and his team had anticipated.

Results of a recent study indicated that hyperbaric oxygen therapy significantly relieved symptoms of fibromyalgia.

The guidelines were created using a panel of rheumatologists, orthopedic surgeons, and patients.