Sjögren's Syndrome

Promising results of the phase 2 and 3 trials offer hope for patients with chronic and debilitating autoantibody-driven diseases.

Because Sjögren's Syndrome is often undetected or misdiagnosed, investigators developed the Sjögren's Syndrome Screening Questionnaire (SSSQ).

There were no differences in the occurrence of clinical characteristics between the subset of patients with and without neurological involvement, however disease activity was slightly higher in patients with neurological involvement than those without. Additionally, anti-SSA antibody was significantly higher in patients with neurological involvement and anti-SSB autoantibody was lower.

The use of abatacept did not lead to significant improvements in the disease status of patients with primary Sjögren's syndrome and in fact, it was essentially no better than placebo treatment, shows the first randomized, double-blind trial on abatacept for Sjögren’s.

September is more than back to school and the arrival of pumpkin-spice-flavored everything. It is also Rheumatic Disease Awareness Month, a national effort created by the American College of Rheumatology (ACR) in 2016 to bring attention to the more than 100 conditions that fall under the umbrella of rheumatic disease.

Women who have primary Sjögren’s Syndrome also have decreased lifetime exposure to estrogen, a new study has determined.

Women who have primary Sjögren’s Syndrome also have decreased lifetime exposure to estrogen, a new study finds.

Sjögren’s Syndrome affects American Indians at a higher rather rate than other ethnic groups, but the lack of classically-associated disease symptoms makes diagnosis difficult, new research shows.

French researchers identified a specific phenotype along with predictive factors.

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Find out how much you know about one of the most difficult chronic autoimmune disorders to manage.

Sjogren’s fails a clinical trial with rituximab and a cost analysis. Even with a significant discount, it’s still not cost effective.

In this case study, Dr. Litvin presents a complicated case of neuromyelitis optica (Devic’s disease), a rare inflammatory autoimmune CNS disease affecting the spinal cord and optic nerves.

The first-ever treatment guidelines for systemic Sjogren’s syndrome have been issued highlighting the need to alleviate symptoms, improve quality of life and prevent further damage.

The American College of Rheumatology and the European League Against Rheumatism have published an international set of classification criteria for primary Sjögren's syndrome.

Saying the Guidelines fill a “significant clinical void,” the organization celebrated awareness of the rheumatic condition with a series of stringently approved recommendations for its treatment.

Clinicians should pay more attention to neurological signs in patients with high-activity primary Sjogren’s Syndrome or those with prior neurological involvements.

B-cells that are active in lupus may also play a role in Sjögren’s syndrome. A new study finds that the same B-cell depleter drug, belimumab (Benlysta) approved for lupus, may also benefit Sjögren’s patients.

ACR2013: Highly specific and sensitive for Sjögren's syndrome, ultrasound of the salivary gland can also benefit the accuracy of the new ACR criteria for the disorder.

Sjogren syndrome affects up to 4 million Americans. There is no cure, but the symptoms-mainly dry eyes and dry mouth-can be relieved.

Meijer JM, Schonland SO, Palladini G, et al, University of Groningen, Groningen, theNetherlands, and other centers. Sjogren's syndrome and localized nodular cutaneousamyloidosis: coincidence or a distinct clinical entity? Arthritis Rheum. 2008;58:1992-1999.