Systemic Lupus Erythematosus

LFA-REAL offers a straight-forward evaluation for lupus-affected organ systems, a study shows.

For systemic lupus erythematosus patients prescribed glucocorticosteroids, mortality has been found to be more frequent than in patients not prescribed glucocorticosteroids, researchers say.

There are few tests to accurately assess the degree and effects of lupus in children, but Ped-ANAM proves to be a promising option.

Lupus patients who receive healthcare at more than one location face a greater risk of infection and comorbidities, research shows.

Diagnosed with systemic lupus erythematosus and chikungunya, a woman embarks on a cross-continent trip for treatment and diagnosis at a city hospital.

Cryptococcal meningitis infections in systemic lupus erythematosus (SLE) patients often go misdiagnosed, researchers find.

Age and cumulative glucocorticoid exposure are key risk factors for low bone mineral density in systemic lupus erythematosus.

For high risk patients with systemic lupus erythematosus, teriparatide and denosumab may be an option for patients who have failed bisphosphonates. Here are some key points you need to know.

Bone loss could affect as many as 31 percent of SLE patients. This article sums up the treatment options from first-line bisphosphonate recommendations to emerging treatments like abaloparatide.

In this Q&A, Rheumatology Network speaks with Dr. Barbara Vilen who is making strides in both basic and translational research that may lead to new therapeutic targets for lupus.

In patients with CNS lupus, early evidence shows the presence of the development of dementia, says Dr. Yehuda Shoenfeld of Israel. "Lupus is a disease of young females, so it's not elderly females with dementia at this age."

The little-understood antibody immunoglobulin E (IgE) plays a previously unknown role in systemic lupus erythematosus, study in Nature Immunology finds.

Women may be far more likely than men to be diagnosed with SLE, but research suggests that at diagnosis, men with the disease may be worse off.

A Phase II trial of a new monoclonal antibody drug shows promise for a potential new treatment for lupus.

A consensus definition of a lupus low disease activity state appears to predict improved outcomes among patients with systemic lupus erythematosus.

A new study in Nutrition Journal shows that patients suffering from systemic lupus erythematosus (SLE) demonstrated significant improvement by taking fish oil supplements.

Social stressors, such as being treated poorly in a doctor’s office, can lead to negative disease outcomes, particularly among black women with lupus, a new study shows.

Hand deformities seen in Jaccoud's arthropathy are the result of soft-tissue abnormalities, not the destruction of bone joints seen in rheumatoid arthritis.

New guidelines issued at EULAR 2015 outline ways to reduce risks of complications for pregnant women with SLE and antiphospholipid syndrome. Details here.

Not all cases with rheumatic disease turn up in the rheumatology literature, of course. Test your diagnostic skills on these four puzzlers from other journals. (We present brief descriptions only, with hyperlinks to the original reports.)

IgG4 levels were low in this study for only systemic sclerosis and Sjögren's. But other patterns suggested aberrant immune regulation.

For patients diagnosed with systemic lupus erythematosus (SLE) finding relief for their symptoms can make a large difference in their quality of life.

(ACR2014) Another Rheumatology Network Editorial Board member weighs in: Christopher Collins MD saw reason for great encouragement in a report about an interferon-α blocker for systemic lupus erythematosus.

(ACR2014) A team from Rush University says their new 10-point instrument developed should be useful to track lupus disease status for trials and in the clinic.

(ACR2014) Early comparisons of patients with rheumatic disease who use marijuana with those who don't show that the practice is not associated with better pain relief. But it is associated with some "sobering" consequences.