Rheumatoid Arthritis

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EULAR 2013: Two-year data from a head-to-head comparison of abatacept and adalimumab show them comparably effective for rheumatoid arthritis. But the former is less costly with fewer noteworthy adverse effects.

Patients with rheumatoid arthritis are at considerably increased risk of asymptomatic carotid artery disease, but standard scores have proven poor predictors of their actual cardiovascular risk. Special vigilance is warranted for these patients.

Research published within the past year has increased and refined support for the concept that this autoimmunity may arise initially in mucosal surfaces, predominantly the lung, the oral cavity, and the digestive system, prompted by the presence of microbes.

A closer look at racial disparities in treatments for rheumatoid arthritis and osteoarthritis show nuanced explanations for why African Americans are less willing to undergo drug therapy and surgery. More careful and clearer communication may go a long way toward closing the gap.

Refining the ample evidence that rheumatologists and their rheumatoid arthritis patients disagree on the severity of symptoms, new studies reported at ACR2012 point toward better definitions of disease status, and a way to identify patients for whom treatment targets may need to be reconsidered.