Rheumatoid Arthritis

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Combining results from studies involving nearly 12,000 rheumatoid arthritis patients finds the fusion protein etanercept less likely than other TNF inhibitors to be discontinued due to infections.

Explanations for the "gender factor" in rheumatoid arthritis risk now include factors unique to the immune response among women, phenomena specific to pregnancy, and perhaps environmental factors including cosmetics.

rheumatoid arthritis

The DAS28 disease-activity score has made the transition from research to clinic, but in some circumstances it may be misleading. A tool developed by a rheumatologist can help you explore how changes in components like ESR affect the score in unexpected ways.

Cardiovascular risk is known to be increased among patients with rheumatoid arthritis (RA), but the interplay between inflammatory and cardiovascular causes and the possible role of medications muddle the picture. No wonder, perhaps, that rheumatologists have difficulty managing this risk. Here, some guidance from experts on the question.

There's limited study of whether disease-modifying drugs for rheumatoid arthritis, with the exception of methotrexate and anakinra, present a risk to a fetus. However, curiously, adverse pregnancy outcomes may increase a healthy mother's risk for developing RA.

Tocilizumab (Actemra) appears to dampen inflammation, increase hemoglobin, and improve inflammatory anemia in rheumatoid arthritis (RA), judging from post hoc analysis of a randomized late-stage clinical trial.

A study from the Netherlands has found a range of minimum serum levels of adalimumab that are associated with a good clinical response in rheumatoid arthritis. As in other studies, adding methotrexate helps.

ACR 2013: Debates about drug costs in rheumatoid arthritis dominated discussions at ACR this year, and one session was formally billed a debate. Will less-costly triple therapy someday be mandated for early RA?