Rheumatoid Arthritis

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Bone erosions found at a rheumatoid arthritis (RA) patient’s baseline exam are harbingers of future joint damage and more severe disease. As to why this is so, new studies offer only hints.

Numbers in randomized drug trials were too small to amass enough adverse events to settle the issue, but combined they show an increased hypertension risk for the tumor necrosis factor inhibitors used to treat rheumatoid arthritis.

For treating rheumatoid arthritis not responsive to methotrexate, DMARD combinations beat monotherapy but at greater risk, a summary of recent evidence observes. In another, reviewers disagree about triple therapy.