Lupus

A systematic review and meta-analysis presented at ACR Convergence 22 provide insight into the effects of belimumab in patient populations with cutaneous lupus erythematosus, with or without systemic lupus erythematosus.

A significantly larger portion of patients in the telitacicept 160 mg achieved SR14 response compared to the placebo group.

Hamilton and his team aim to reduce intensive and often unnecessary screening, including weekly fetal cardiac ultrasounds, via autoantibody identification.

The number of autoantibodies and congenital heart block pregnancies expanded to approximately 30 different autoantibodies to different targets near term.

Investigators believe it is important to understand the patient's perspective regarding vaccine concerns and combining that perspective with stakeholders to prioritize topics for future research.

Bahar Moghaddam, MD, discusses the impact of arthritis worldwide, recent drug approvals, and the importance of early diagnosis and management of rheumatic diseases.

A significantly higher number of patients receiving voclosporin achieved good renal outcome when compared with placebo.

Investigators aimed to assess self-reported changes in physical activity during the COVID-19 pandemic.

"Infections are one of the key determinants of early morbidity and mortality of patients with SLE, strongly linked to disease activity and immunosuppression."

Preventing chronic damage accrual is one of the top treatment targets, as it is linked to increased mortality and decreased quality of life.

A statistically significant elevated risk of SLE was shown among women with low sleep, depression, and bodily pain when compared with those without these concomitant issues.

Drs. Anne E. Winkler and Kristi V. Mizelle share practice pearls to optimize the management of patients of patients diagnosed with lupus.

Experts in rheumatology provide an overview of novel treatment options currently under investigation for the treatment of systemic lupus erythematosus and lupus nephritis.

Kristi V. Mizelle, MD, MPH, FACR comments on long term efficacy data on the use of biologics in lupus, with a focus on preventing organ damage.

"Surveys of patients with SLE and other autoimmune and inflammatory rheumatic diseases have identified vaccine hesitancy in up to 50% of patients, which may be related to concerns about side effects, potential disease flares, or lack of data among patients with SLE.”

Findings demonstrate the utility of machine learning in aiding clinical risk stratification within a complex patient cohort.

The findings of this study of anti-CD19 directed CAR T cell therapy offers new hope for the most severe and refractory cases.

Anne E. Winkler, MD, PhD, MACP shares her approach to treatment in patients with lupus post treatment with immunosuppressants with a focus on treatment sequencing.

Drs Anne E. Winkler and Kristi V. Mizelle explore relevant treatment options for a patient with lupus nephritis and highlight efficacy and safety considerations.

Throughout the pandemic, rheumatologists have been concerned that their patients may be at risk of developing more severe forms of the COVID-19 disease as a result of their rheumatic disease or treatment.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending September 24, 2022.

Bonnie L Bermas, MD, discusses the ways in which the Supreme Court decision to overturn Roe v Wade will change the way rheumatologists are able to care for their patients.

An expert in lupus management provides insight into her treatment approach for a 24-year-old African American female diagnosed with lupus nephritis.

Lupus Case Scenario: Patient History and Presentation

Fatigue, a highly multifactorial manifestation of lupus, can be related to disease activity or independent of the disease itself. Investigators determined whether fatigue could be a significant confounder of Physician Global Assessment ratings.