“The most important take home message for rheumatologists is that we can predict lack of response to methotrexate by analyzing the fecal microbiome of patients before the initiation of the treatment,” said Jose Scher, MD, rheumatologist from the Department of Medicine, Mount Sinai School of Medicine, New York.
Although the stakes couldn’t be higher and the promotion of healthy behavior is paramount, the emphasis on BMI and weight is likely to yield little benefit. The Association for Size Diversity and Health (ASDAH) developed Health at Every Size (HAES) to take the focus off of weight change and place it more squarely on health, thus supporting people of all sizes to take care of themselves and improve health outcomes.
Investigators compared a self-directed, stepped exercise program to improve symptoms of knee osteoarthritis in randomized trial to an education-based approach.
Previously proven to be an effective and well-tolerated treatment for patients with RA, baricitinib can also help patients reduce joint damage progression and erosion.
The outcomes with COVID-19 infection in patients with rheumatic or musculoskeletal disease are better in those infected later in the pandemic.
Coupled with the fact that there were no new safety concerns identified, these findings further solidify the safety and effectiveness of abatacept for RA patients.
The study is the first randomized trial to examine the comparative benefits and safety of biological drugs with different modes of action versus active conventional treatment.
A phase 2 trial from investigators in the UK suggests use of denosumab, a human monoclonal antibody, could drastically reduce the rate of revision procedures after hip replacements.
An analysis of data from more than 1.2 million Korean women offers insight into how reproductive factors might impact fracture risk among postmenopausal women.
The reviewers find persistent disease activity and flares despite progress to date. In addition, they point to the persistence of glucocorticoid treatment dependency, comorbidity burden, reduced health-related quality of life, and inconsistent access to high-quality care.
“Bone mineral density screening rates remain low, as do calcium/vitamin D supplementation and primary prophylaxis with anti-osteoporotic therapy," lead author Eileen Rife, MD, said.
An analysis of 34k patients over more than a decade indicates living alone after a hip fracture was associated with a 37% increase in mortality risk among men and a 23% increase in risk among women.
The results of a study presented at ACR 2020 demonstrate that a greater proportion of patients were initiated on denosumab compared with bisphosphonates for the first time—18.5% compared with 16.9%— in 2018.
The US and the world must appreciate the role of the pharmaceutical industry—the investigators, physicians and business leaders—who are rescuing the world from COVID-19. It’s the medical breakthrough of our lifetime.
The IL-23 inhibitor is shown to improve disease activity across joint and skin symptoms.
In part 1 of this article series, Dr. Concoff dusts off the crystal ball to envision the future of the practice of rheumatology, in particular the role of telemedicine during the COVID-19 pandemic and beyond.
Some studies have suggested an increase in the incidence of neuropsychiatric disorders in rheumatic patients may be due to the immunological mechanisms of the disease itself.
Long-term outcomes in systemic lupus erythematosus have improved over time, but unmet needs include glucorticoid dependency and comorbidity burden.
This article features the top 5 stories in Endocrinology Network's coverage of osteoporosis management in 2020.
Although there is no indication that older adults with chronic inflammatory conditions are at higher risk for developing dementing disease, the likelihood is that mild cognitive impairment will show up in your office.
Some of the latest developments in the use of these diagnostic tools for psoriatic arthritis were presented the annual meeting of the American College of Rheumatology Convergence 2020 in November.
“The main take home message is to pay attention to the prevention and treatment of GIOP while prescribing steroids to the patients because the side effects is steroids are not benign," Shikha Singla, MD, said.
The approval was based on findings from the Belimumab International Study in Lupus Nephritis (BLISS-LN) study.
Ixekizumab appears to provide significantly greater simultaneous joint and skin improvement for patients with psoriatic arthritis than adalimumab and doesn’t require combination with methotrexate to boost its efficacy.
Findings from a study presented at ACR 2020 showed a clear difference in co-morbidities and medication use associated with osteoporosis at different lumbar levels. Here, a Q&A with the co-author.
Patients who had received tofacitinib combination therapy may be able to discontinue methotrexate.
The Centers for Medicare & Medicaid Services (CMS) has approved the final physician fee schedule for cognitive care reimbursement in the 2021 Medicare Physician Fee Schedule (MPFS).
The American College of Rheumatology (ACR) issued a statement on Wednesday objecting to a new Centers for Medicare and Medicaid Services (CMS) drug pricing rule the Trump Administration issued in November.
Young men with distal radius fracture are likely to have hormonal imbalances suggests the first study to look at sex hormone levels in younger men experiencing fractures.
Non-heterosexual minority men have a greater risk of poor bone health than heterosexual men, and this risk appears to be independent of lifestyle and psychosocial factors, suggests a study published in the American Journal of Human Biology.
