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Musculoskeletal pain is common. In one analysis, 33% of adults reported musculoskeletal pain from overuse as a chief complaint. Morbidity resulting from musculoskeletal pain contributes to 29% of lost workdays because of illness and is second only to cardiovascular disease in terms of economic burden

Early and accurate gout diagnosis and disease management are essential. Making the clinical diagnosis takes into consideration the differential diagnosis supported by the use of clinical, serological, and diagnostic studies.

Fibromyalgia syndrome (FMS) is a complex disorder of chronic, widespread pain and tenderness usually accompanied by numerous other symptoms, including fatigue, cognitive dysfunction, nonrestorative sleep, depression, anxiety, and stiffness.

Systemic sclerosis (SSc), or scleroderma, is a chronic connective-tissue disease that has a multitude of clinical manifestations. These authors offer a guide to recognition and pathogenesis, as well as counsel about management.

Chondroitin sulfate significantly decreases pain and improves hand function in patients with hand osteoarthritis (OA), according to new research reported by the American College of Rheumatology (ACR). The agent also improves grip strength and relieves morning stiffness.

Familiarity with metatarsalgia, an array of disorders that cause pain to the forefoot, enhances the clinician's ability to make the proper diagnosis.

Recombinant uricases provide an exciting new therapeutic option for gout, but there are limited data for their use in the elderly.

Multidisciplinary management of fibromyalgia syndrome, including pharmacological and nonpharmacological interventions, is optimal. Exercise may improve patients’ symptoms and quality of life, but an exercise program may be challenging because of pain, stiffness, and fatigue.

A 10-year-old boy injured his left elbow during football practice. He subsequently had pain with normal range of motion of the elbow. He had minimal tenderness over his olecranon but no joint swelling, bruising, or palpable mass

Regional cancellous bone mineral density (BMD) can be approximated from Hounsfield units (HU) measured on CT examinations using automatic exposure control; this information is reliable and follows a predictable pattern with increasing age.

Accurate diagnosis of elastofibroma dorsi may be achieved with a proper clinical history, knowledge of the characteristic site of the lesion, and typical imaging findings to avoid unnecessary biopsy and surgery.

Quadriceps (rectus femoris) strains are common among athletes, usually after kicking or sprinting. Learn about imaging tests for diagnosis and the exercises that encourage healing and rehabilitation.

Joint aspiration may be used for diagnosis or for relieving pressure, and joint injection may be used for treatment. Physicians can easily become proficient in aspiration and injection techniques. Indications for aspiration include both acute and chronic arthritis; there are few absolute contraindications. Intra-articular injections of medication usually are an adjunct to other treatment modalities.

NSAIDs are among the most frequently used and prescribed medications in the management of musculoskeletal pain and injury. Many physicians consider them to be the medication of choice. However, a number of studies have questioned the value of NSAIDs in the healing process of bone, muscle, tendon, and ligament injuries

Misdiagnosis of fibromyalgia syndrome (FMS) occurs frequently in the clinic. In our case report, a 27-year-old woman with recurring neck pain and stiffness had received a diagnosis of cervical spondylosis, but later a definitive diagnosis of FMS was made. Misdiagnosis of FMS has occurred with various other diseases.

A 23-year-old woman who reported experiencing direct trauma to her right knee on a hard surface 3 months earlier was admitted to the arthroscopy unit with complaints of decreased range of motion (flexion, 90°; extension, 75°) and intractable pain.

A new treatment for a disabling hand condition-Dupuytren disease, or Dupuytren contracture-can restore a person’s ability to perform everyday tasks, according to Hands: Strategies for Strong, Pain-Free Hands, a new edition of the Special Health Report from Harvard Medical School. The report describes the causes of and treatments for a variety of conditions that can cause hand pain and features information on hand exercises.