Rheumatoid Arthritis

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Early rheumatoid arthritis is, in part, defined as having symptoms for at least six months. Beyond six months, it's considered established rheumatoid arthritis. But diagnosing early rheumatoid arthritis is not that straightforward. Serologic tests can confirm a clinical diagnosis, but these tests aren't always reliable and can be negative in about 50 percent of rheumatoid arthritis cases. In this quiz, we focus on the diagnosis and treatment of early rheumatiod arthritis.

What is the connection (if any) between coronavirus and autoimmune diseases?  In this slideshow, we feature some points of view from rheumatology experts in the field, including Dr. Jean Liew of the University in Washington, Seattle, who told CreakyJoints that patients with inflammatory arthritis are probably more susceptible to the coronavirus and are at higher risk of complications like pneumonia.

Biologics Help Maintain Bone Density in RA

Bone mineral density was preserved over a three-year period in patients with rheumatoid arthritis treated with biological/targeted synthetic disease-modifying antirheumatic drugs (DMARDS) but declined in those who received only conventional-synthetic DMARDs, say researchers recently writing in Rheumatology.

Study Confirms Skin Cancer Risk with Methotrexate

A double-blind, placebo-controlled, randomized clinical trial has confirmed that low-dose methotrexate is associated with an increased risk of skin cancer, according to a study published this week in the Annals of Internal Medicine.

Ideal Clinical Pathway Reduces RA Pregnancy Risk

Women with rheumatoid arthritis who adhered to a defined program involving diagnostic, therapeutic, and prenatal care recommendations restored the risk of adverse pregnancy outcomes to that expected in the general population, say researchers recently writing in Arthritis Care & Research.

Disease activity measures still don’t appear to be entirely aligned with patient perceptions of pain and disease activity, shows a study featured in today’s news roundup. Researchers writing in Rheumatology say that condition improvements seen in objective measures of rheumatoid arthritis (RA) disease activity over the past three decades, do not match improvements in patient reported outcomes such as mental health, functional disability, overall disease activity, pain and vitality/fatigue. Learn more about this and other recently published studies on rheumatoid arthritis.

High Dose Flu Shot Best for Rheumatoid Arthritis

In patients with seropositive rheumatoid arthritis, high-dose trivalent inactivated influenza vaccine (HD-TIV) is safe and more immunogenic than standard-dose quadrivalent influenza vaccine (SD-QIV), say researchers writing in The Lancet Rheumatology.

Rheumatoid arthritis patients have an increased risk of developing cardiovascular disease, yet rheumatologists and primary care physicians who treat RA patients sometimes miss the signs and symptoms of CVD in their patients. Learn more in this slideshow.

Placebo effect in RA

The placebo response in clinical trials for rheumatoid arthritis appears to have grown over the last two decades with patients exhibiting significant improvements in pain scores with placebo treatment.

The JAK inhibitor upadacitinib was approved last August for the treatment of moderate to severe rheumatoid arthritis. In this quiz, we focus on findings from a recent phase three clinical trial that tested different doses of this new oral medication. Test your knowledge of upadacitinib in this quiz.

In this slideshow, we feature results from some noteworthy rheumatoid arthritis studies that were recently published: improved patient-reported outcomes in refractory rheumatoid arthritis with use of a JAK inhibitor, mortality risk with coronary microvascular dysfunction similar in rheumatoid arthritis and diabetes, prescriber preference affects the length of time a patient takes a conventional synthetic DMARD before switching to a biologic DMARD, and more.