Gout

A new study found febuxostat can effectively delay the progression of kidney function deterioration in patients with gout.

The meta-analysis demonstrated gout with high blood uric acid levels significantly increases the risk of experiencing angina attacks.

Patients placed in the intervention group reported significant improvements in gout knowledge levels over time compared with controls throughout the 24-week study period.

Monosodium urate deposits significantly increased the risk of major cardiovascular events in patients with gout and hyperuricemia.

Among the nurse-led cohort, 83% of patients with gout achieved target p-urate levels and 98% continued treatment with urate lowering therapy.

The incidence of gout was 2.9 per 1000 patient-years, which dropped by 30% at the beginning of the COVID-19 pandemic.

Strategies designed to promote medication adherence were found in only 1 out of 3 websites.

An observational study in the UK investigated the risk of adverse events related to colchicine prophylaxis after receiving allopurinol for gout.

After being prescribed another urate lowering therapy for ≥ 30 days, only 51.0% of patients were able to achieve SU < 6 mg/dL.

A propensity score-matched, new-user analysis suggests SGLT2 inhibitors may reduce gout risk in type 2 diabetes patients relative to other second-line therapies.

NSAID use decreased the odds of a cardiovascular event by 12% in patients with gout.

Patient-led urate monitoring supports adherence to urate-lowering therapy and helps attain target concentrations among individuals with gout.

Alkaline water significantly reduced VAS pain scores among patients with gout.

For those with a family history of gout, the proportion of grade ≥ 2 left ventricular diastolic insufficiency was markedly higher compared with patients without family history.

Patients with gout who had poor health literacy were more likely to experience ≥ 2 flares within the previous 12 months.

Kenneth Saag, MD, explores the clinical significance of a study demonstrating treatment with pegloticase leads to bone remodeling in patients with gout.

A meta-analysis found febuxostat was linked to a greater risk for acute coronary syndrome and atrial fibrillation than allopurinol among Asian patients with and without gout.

A new review considers how SGLT2 inhibitors like dapagliflozin and empagliflozin have been shown to clinically improve gout while reducing its cardiometabolic and renal comorbidities.

Results showed co-administration of methotrexate with pegloticase led to similar rates of urate-lowering response and adverse events in patients with and without CKD.

A comparison of the urate-lowering therapies shows discrepancies in short- and long-term use outcomes.

From 1990 to 2019, the prevalence, incidence, and disability-adjusted life years of gout worldwide increased by 22.4%, 18%, and 22.2%, respectively.

Test your knowledge of the ACR's guideline for the management of gout with this quiz!

Findings provide insights into the current state of healthcare utilization for patients with gout living in South Korea.

Patients with gout and negative DECTs for monosodium urate crystal deposition exhibited milder disease and a lower comorbidity burden.

Often considered a cause of symptom onset in musculoskeletal conditions, a new study found that weather factors do not appear to be a risk factor for pain.