News

Researchers Try to Reverse the Aging Process for Arthritic Joints

ACR Annual Meeting:  Single intra-articular doses of UBX0101 of up to 4 mg were well-tolerated by patients with painful knee osteoarthritis, according to a study presented at the annual meeting of the American College of Rheumatology in Atlanta on November 12. The treatment is in development, but if it pans out, it may reduce the effects aging on arthitic joints.

Emapalumab Shows Promise in Macrophage Activation Syndrome

ACR Annual Meeting:  In a small study, patients with macrophage activation syndrome (MAS) receiving emapalumab (Gamifant, Sobi) achieved complete response, according to data presented at the annual meeting of the American College of Rheumatology in Atlanta on November 12.

Cannabis Use Up Among Patients with Rheumatic Diseases

ACR Annual Meeting:  Cannabis use among patients with rheumatic diseases has increased since 2014, and those who tried cannabis tended to have worse pain, disease activity, and symptoms and were taking more analgesics, according to a study presented at the annual meeting of the American College of Rheumatology in Atlanta on November 13.

Calcium Pyrophosphate Deposition Disease Linked to Major CV Events, Death

ACR Annual Meeting:  Patients with calcium pyrophosphate deposition (CPPD) disease may be at an increased risk of major adverse cardiovascular events along with a higher mortality rate compared to those without the disease, according to a study presented at annual meeting of the American College of Rheumatology in Atlanta on November 12.

Active Conventional, Biological Therapy Show Similar RA Remission Rates

ACR Annual Meeting:  A large proportion of patients with rheumatoid arthritis achieved remission with either active conventional therapy or with one of three different biologic therapies, certolizumab, abatacept and tocilizumab, after 24 weeks of treatment, according to a study presented at the annual meeting of the American College of Rheumatology in Atlanta on November 12.

EU Consensus Statement on Combined Therapy with Methotrexate

ACR Annual Meeting:  Methotrexate should be continued in most patients with active rheumatoid arthritis when biologic or targeted synthetic therapy is initiated, EU researchers reported in a poster presentation on November 12 at the annual meeting of the American College of Rheumatology in Atlanta.

Ustekinumab Linked to Lower Serious Infection Rates in Psoriasis and Psoriatic A

ACR Annual Meeting:  Compared with seven other biologics and a phosphodiesterase-4 inhibitor, the anti-IL-12/23 biologic ustekinumab was associated with a generally lower risk of serious infection requiring hospitalization in psoriasis or psoriatic arthritis patients, researchers reported on November 12 at the American College of Rheumatology annual meeting in Atlanta.

Olokizumab May Offer New Option for RA Patients

ACR Annual Meeting:  The anti-IL-6 agent olokizumab was safe and effective when added to methotrexate in patients with rheumatoid arthritis in a phase three randomized controlled trial, researchers reported on November 12 at the American College of Rheumatology annual meeting in Atlanta.

ACR Annual Meeting: Patients with early rheumatoid arthritis and serological biomarkers of a poor prognosis who initiated treatment with abatacept plus methotrexate, sustained remission across all arms of a 48-week dose de-escalation trial, though the full combination produced the best maintenance, researchers reported November 12 at the American College of Rheumatology annual meeting in Atlanta.

Gout Attacks Intensify with Heart Failure

ACR Annual Meeting:  Gout patients who are admitted to the hospital with worsening heart failure, go on to have gout attacks during hospitalization leading to longer hospital stays, researchers reported November 10 at the annual meeting of the American College of Rheumatology in Atlanta.

Golimumab Study Shows Lasting Improvements in Psoriatic Arthritis

ACR Annual Meeting:  Intravenous golimumab produced lasting improvements in health-related quality of life for psoriatic arthritis patient one year post treatment, researchers reported on November 11 at the American College of Rheumatology annual meeting in Atlanta.

Here's why there are no new treatments for lupus

ACR Annual Meeting: At the American College of Rheumatology annual meeting in Atlanta today, Dr. Konstantinos Tselios of the University of Toronto addresses the challenges associated with developing new treatments for systemic lupus.

Abatacept Monotherapy Effective in JIA

ACR Annual Meeting:  Monotherapy with abatacept was safe and effective in patients with polyarticular juvenile idiopathic arthritis who couldn’t tolerate or didn’t respond to methotrexate, researchers reported November 11 at the annual meeting of the American College of Rheumatology in Atlanta.