Psoriatic Arthritis

Rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis are linked with an increased risk of complications from total knee arthroplasty, AAOS 2016 study finds.

Research points to evidence showing that microorganisms inside our bodies could play a role in the development of arthritis, but it could also be a new therapeutic pathway.

Blood analysis in patients with inflammatory rheumatic diseases such as psoriatic arthritis indicates that biologic medications do not reduce the efficacy of anti-pneumococcal polysaccharide vaccine, and that patients with such conditions may not need to be vaccinated more frequently than others.

Biologic drug secukinumab (Cosentyx/Novartis), already FDA approved in January 2015 to treat chronic plaque psoriasis, has now been approved for two new indications: the treatment of active ankylosing spondylitis (AS) and active psoriatic arthritis (PsA).

A new patient registry analysis assessed whether there were any significant differences in outcome between combination therapy and monotherapy in patients with psoriatic arthritis.

The development pipeline for psoriasis in summary.

New research clarifies the presentation and treatment of nail psoriasis for rheumatologists, dermatologists and general practitioners.

The first level in management of nail psoriasis is patient education.

Psoriatic arthritis is associated with an additional increase in cardiovascular disease. One hypothesis shows that rheumatic diseases and atherosclerosis may be related due to an inflammatory mechanism.

T cell activator associated with psoriatic arthritis but not psoriasis.

Longer intervals between injections of anti-TNF drugs in patients with psoriatic arthritis is "safe, effective, cost-effective, and facilitates patient compliance," according to researchers.

A study of patients undergoing total hip arthroplasty found that patients with psoriatic arthritis face no greater risk of poor outcomes than patients who get hip replacements because of osteoarthritis.

Study shows that patients with psoriatic arthritis and cutaneous psoriasis could be good candidates for total hip replacement.

Regulators in the UK have decided not to recommend apremilast as an alternative to DMARD therapy in patients with psoriatic arthritis.

Researchers have found further links between vitamin D deficiency and chronic inflammatory rheumatic diseases such as psoriatic arthritis.

Distinguishing between different types of childhood arthritis is not always easy.

Psoriasis and psoriatic arthritis have long been associated with cardiovascular disease and deaths, but now a large population study from Taiwan indicates the danger of cardiac arrhythmias is increased independently of traditional risk factors such as coronary disease and high blood pressure.

Analysis of a population-based cohort indicates that patients with psoriasis and psoriatic arthritis face an elevated risk of developing heart arrhythmias such as atrial fibrillation.

This overview of NSAIDs, corticosteroids, DMRDs, PDE4 inhibitors, and biologic agents offers recommendations for first-line options for mild and moderate-to-severe psoriatic arthritis.

Physical trauma, especially a deep trauma to bones and/or joints, appears to increase the risk of psoriatic arthritis by as much as 50% in patients with psoriasis.

A new study suggests the importance of evaluating the vitamin D3 status and screening for comorbid conditions in patients with psoriasis or psoriatic arthritis.

Although moderate alcohol intake is linked to health benefits, a high consumption can have a negative effect on women.

A small prospective study finds that patients with psoriatic arthritis eventually revert to disease if TNF-alpha drugs are discontinued, sometimes as much as 6 months later.