Spondyloarthritis

A new study of long-term data demonstrates that infliximab and golimumab are both effective, safe treatments for symptoms of ankylosing spondylitis.

Reactive arthritis is an inflammatory joint arthritis largely characterized by joint inflammation triggered by infection. To date, no diagnostic or classification criteria have been established, but in 2014, the American College of Rheumatology issued general treatment guidelines. In this article, we highlight a new review article on treatments for reactive arthritis.

A 40-year-old man presents to his primary care doctor complaining of pain in his ankles, knees, feet, heels, lower back and buttocks. What's your diagnosis?

Remission is unlikely in non-radiographic axial spondyloarthritis without biologic therapy. Adding certolizumab to background therapy can lead to significant improvements in disease activity compared to placebo, researchers find.

In a recent edition of Frontiers in Immunology, Dr. Walter Maksymowych, University of Alberta, reviews the use of biomarkers for diagnosis and prognosis in axial spondyloarthritis. Learn more in this summary.

Children affected by juvenile idiopathic arthritis, manifesting as non-systemic polyarthritis, sacroilitis or enthesitis, have a number of therapeutic options available. In this article, we outline the options.

The COAST-X trial evaluated the safety and efficacy of ixekizumab for the treatment of non-radiographic axial spondyloarthritis (nr-axSpA).

Axial spondyloarthritis (axSpA) is never a straightforward diagnosis. In this slideshow, we highlight 11 disease manifestations associated with axSpA.

Delays in diagnosing axSpA are troubling, write the authors of a report in the journal Rheumatology. Delays of up to 10 years have been reported. Not all physicians may be familiar with the signs and symptoms of axSpA.

Physiotherapy, exercise and pain medications should be part of the treatment plan to improve the quality of life of patients suffering from stiffness associated with axial spondyloarthritis.

Certolizumab pegol (Cimzia) is the first FDA-approved treatment for the condition.

The cause of discovertebral lesions in ankylosing spondylitis may be due to infectious, inflammatory or traumatic etiologies suggest researchers writing in the Journal of Rheumatology. They examined the most prevalent-and conflicting-theories associated with this medical mystery.

A recent study suggests that the appearance of hidradenitis suppurativa may be another associated manifestation that can predict a more severe course of axial spondyloarthritis.

A recent study published in the Annals of the Rheumatic Diseases shows that ankylosing spondylitis is linked to an increased risk for venous thromboembolism and deep vein thrombosis.

Smoking in axial spondyloarthritis doesn't appear to impact treatment with TNF inhibitors despite the status of disease severity, a study shows.

Lack of trust in physicians, lack of information about biologics, medicine substitutions and the search for alternative therapies are among the reasons patients turn to the internet, a new study shows.

A well-established treatment for psoriasis, psoriatic arthritis, and Crohn’s disease failed to work in axial spondyloarthritis patients, a study shows. But the study's failure may tell us more than not.

Researchers writing in PLOS One report that patients with ankylosing spondylitis have a significant higher prevalence of dementia and Alzheimer’s dementia than the general population.

Half of patients with axial spondyloarthritis have both the axial and peripheral forms of the disease, which may explain why these patients have higher disease activity, researchers write in RMD Open.

Researchers writing in Arthritis Research and Therapy describe the results of a randomized clincal trial in which most patients with Ankylosing spondylitis maintained low disease activity or remission with standard or reduced TNFi dose schedules.

T1-weighted MRI may be a highly specific and reliable test for diagnosing SpA.

Vertebral fractures may not be as common in spondyloarthritis as previously thought.

Recent studies assessed the impact of statins on disease activity and compared plain radiography vs MRI for early diagnosis of axSpA.

British researchers examine the impact of axSpA on employment.

Findings from the most extensive study to analyze the association between HLA-B27 status and manifestations of AS.