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“Biomarkers can be used to elucidate normal and pathological processes and to measure biological response to a therapeutic intervention,” investigators stated.

The American College of Rheumatology recommends that a treat-to-target strategy is followed for rheumatoid arthritis. Test your knowledge of how to maximize the potential benefits of this approach with this quiz.

In this Q&A, Gerd R. Burmester, MD, discussed the findings of his study that evaluated the exposure to ixekizumab, outcomes and medical history of patients with active psoriatic arthritis (PsA) who experienced adverse events.

On April 29, AbbVie announced the US FDA had granted approval to upadacitinib 15 mg (RINVOQ) for treatment of active ankylosing spondylitis among adult patients who had inadequate response or intolerance to at least 1 TNF inhibitor.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending April 30, 2022.

investigators initially theorized the drug may positively impact patients with COVID-19 treated with ruxolitinib.

In the interest of receiving a variety of opinions from rheumatologists, we asked several key opinion leaders about their thoughts on treating patients with glucocorticoids, regarding their reputation, benefits, risks, and if they are ultimately more helpful or harmful in the treatment of rheumatic diseases.

“In recent years, the habit of delaying pregnancy because of social and economic reasons has become more common, increasing the possibility of getting pregnant after the onset of the disease," investigators stated. "This fact makes pregnancy a more frequent issue to deal with in the present years.”

An analysis of data from a Cleveland Clinic database indicates calcium supplementation in older adults with aortic stenosis was linked to an increased risk of mortality and worsening aortic stenosis.

Approximately a quarter of RAPID3 assessments, confirmed with 92% accuracy by DAS28 scores, reported patients had low disease activity and could, therefore, postpone routine clinical visits.

Mental and physical illnesses, such as rheumatoid arthritis, are often driven by social, environmental, and economic factors and may affect disease outcomes.

“Understanding the extent of the co-occurrence and identifying factors associated with an increased susceptibility could be relevant to implement case-finding strategies in specific at-risk populations," investigators stated.

A notable percentage of patients with rheumatic diseases, such as psoriatic arthritis, stop taking bDMARDs due to lack of effectiveness and adverse events.

Manuel Francisco Ugarte-Gil, MD, MSc, explains the impact that severe flares have on health-related quality of life for patients with systemic lupus erythematosus.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending April 23, 2022.

Our endocrine month in review spotlights the most popular articles from the past month. This month's top articles include a multipart video series, new diabetes, information on osteoporosis, and more!

On April 20, the UK National Osteoporosis Guideline Group released updated guidance for the diagnosis, prevention, and treatment of osteoporosis, which has received endorsements from the IOF and ESCEO.

Telemedicine is an evolving and helpful tool in how rheumatologists manage their outpatient cohort. However, careful distinction of who can continue to be managed remotely is crucial.

As quality of life (QoL) in patients with psoriatic arthritis (PsA) is significantly lower when compared with patients with psoriasis, one of the main goals of treating PsA is improving QoL.

Infants born to mothers with autoimmune disease had a 16% higher risk of being diagnosed with a mental disorder compared with those who were not prenatally exposed to maternal autoimmune diseases.

Until now, there has been limited information on the long-term safety and efficacy of belimumab in Chinese patients with systemic lupus erythematosus.

An analysis of data from a 5000-patient cohort suggests use of NSAIDs was associated with a detrimental effect on the benefit of clodronate on reducing risk of fracture among older women.

Disease flares in systemic lupus erythematosus are associated with damage. However, the impact of flares on health-related quality of life have not been analyzed.

COVID-19 vaccines and drugs for rheumatoid arthritis (RA) don’t always mix well. How much do you know about how RA medications impact the immune response generated by COVID-19 vaccines?

White a treat-to-target strategy is an important part of managing patients with rheumatoid arthritis, a more controlled implementation with closer follow-up appointments and patient education yielded better outcomes.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending April 16, 2022.

Guidelines lack clear recommendations for osteoporosis management and fall prevention, which may be due to a lack of evidence in the literature.

Understanding the differences between sexes regarding PsA treatment may change the management of PsA in male and female patients and improve outcomes.

Investigators address the need for understanding surrounding the relationship between poor bone health and patients who are hemophilia carriers and those with von Willebrand disease.

“Although the achievement of treatment targets has been associated with improved quality of life and slower disease progression, patients may still experience symptoms and a burden of disease,” investigators stated.