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Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending November 5, 2021.

While approximately 80% of patients with rheumatic disease showed humoral immune response rates following the second dose of the COVID-19 vaccine, these numbers were significantly lower than controls.

Investigators analyzed comorbidities, such as diabetes, which has been historically associated with gout, to determine what role, if any, they played in increasing the risk of lower extremity amputation.

Vibeke Strand, MD, explores her ACR presentation, “Assessing the Relationship of Patient Global Assessment of Disease Activity and Health Related Quality of Life by SF-36 with Other Patient-Reported Outcomes in Rheumatoid Arthritis: Post Hoc Analyses of Data from Phase 3 Trials of Baricitinib.”

Niti Goel, MD, discusses her ACR Convergence presentation entitled, “Depletion of KLRG1+ T Cells in a First-in-human Clinical Trial of ABC008 in Inclusion Body Myositis (IBM).”

Jean Liew, MD, MS, discusses her upcoming ACR Convergence presentation entitled, “SARS-CoV-2 Infections Among Vaccinated Individuals with Rheumatic Disease: Results from the COVID-19 Global Rheumatology Alliance Provider Registry."

Karen H. Costenbader, MD, MPH, discusses her upcoming ACR Convergence presentation entitled, “Year in Review: Clinical Rheumatology."

A propensity score-matched analysis comparing fracture risk associated with the initiation of SGLT2 inhibitors versus GLP-1RAs or DPP-4 inhibitors indicates use of SGLT2 inhibitors was not associated with an increase in risk of fractures in older patients with type 2 diabetes.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending October 29, 2021.

Data show participants with early glucocorticoid use were more likely to be prescribed a biologic by 12 months, in comparison to non-users.

Cassandra Calabrese, DO, examines immunopathogenesis, immunomodulation, COVID-19 vaccinations, and pre-exposure prophylaxis.

Investigators called for the development of health care system structures to better support the exchanging of resources and information.

“Systemic lupus erythematosus is a chronic inflammatory autoimmune disease where a variety of organ complications contribute to an increased risk of premature mortality,” investigators stated.

Interview questions focused on mental and physical health, guidance received by healthcare providers, and the impact of COVID-19 on healthcare access and self-management behaviors.

“Using the strengthening exercises with mHealth may have the potential to reduce pain, improve mobility, functional activity, and activities of daily living among knee osteoarthritis patients who are overweight or obese," investigators stated.

Data show no significant improvement in pain, function and alignment scores over 26 weeks in the PRP injection group, compared to placebo.

Chronic back pain, a common symptom of axial spondyloarthritis that increases disease burden and reduces quality of life, may be improved by subcutaneous injection of secukinumab 150 mg or 300 mg.

The risk of adverse outcomes increased the most in pregnancies with antirheumatic treatment, especially those treated with biologic disease modifying antirheumatic drugs (bDMARDs), when compared with controls.

The rates of adverse events was similar across all 4 indications in comparison to the placebo group.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending October 22, 2021.

A regular fitness routine was associated with less pain and stiffness, as well as an increase in functional capacity, in patients with knee osteoarthritis.

The study examines the impact of antirheumatic treatment on pregnancy outcomes in women with psoriatic arthritis.

A significant number of patients with psoriatic arthritis fail to achieve adequate disease control, resulting in health-related quality of life (HRQOL) impairments.

Dactylitis, a uniform swelling of an entire digit, occurs in up to half of patients with psoriatic arthritis and is sometimes the first manifestation of the condition.

Osteoporosis is a common comorbidity for patients with rheumatoid arthritis. How much do you know about how drugs impact bone health in rheumatoid arthritis?

“Evidence has accumulated on the effectiveness of physical activity to reduce disease-related symptoms such as pain and comorbidity risk in people with rheumatoid arthritis,” investigators stated.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending October 15, 2021.

Approximately a third of systemic lupus erythematosus patients experience ocular involvement, which may be linked to disease pathophysiology.

Investigators analyzed the potential beneficial effect of hydroxychloroquine to prevent COVID-19 infection in patients with rheumatic disease.

“Considering medical appointments, laboratory tests, medications, and indirect costs, juvenile idiopathic arthritis generates elevated costs, which results in a high economic impact for the family,” investigators stated.