The AHA released a statement related to use of oral penicillin for patients with high-risk rheumatic heart disease, including patients with severe mitral stenosis, aortic stenosis, left ventricular systolic dysfunction, or active symptoms of rheumatic heart disease.
Deucravacitinib selectively binds to a unique pocket in the regulatory domain of TYK2 instead of the highly conserved active site of the catalytic domain,” investigators explained. “This leads to targeted inhibition of immune pathways that are central to psoriasis while limiting off-target effects.”
Women were significantly more likely to utilize complementary and alternative medicine strategies, such as yoga, acupuncture, and vitamins, to help manage chronic arthritis symptoms.
Promising results were announced by UCB after a Phase 3 study evaluated bimekizumab for non-radiographic axial spondyloarthritis and met all endpoints.
An analysis of data from more than 50k patients using risedronate or alendronate from Ontario compares the risk of hip fracture and other outcomes during drug holidays.
Bimekizumab, an interleukin 17A (IL-17A) and IL-17F inhibitor, met both primary and secondary endpoints for treating adult patients with non-radiographic axial spondyloarthritis.
Physical activity is known to improve function, quality of life, and pain in rheumatoid arthritis. How has the pandemic affected patients’ participation in physical activity? Test your knowledge with this quiz.
While the goal of rheumatoid arthritis treatment is low disease activity and remission, many patients are apprehensive about changing or escalating RA treatment.
Stephen Balevic, MD, explains hydroxychloroquine PK and exposure-response in pregnancies with lupus and the importance of adhering to treatment both during pregnancy and postpartum.
Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending January 14, 2021.
While investigators were hopeful that duloxetine, an SNRI, would reduce chronic pain in patients with knee osteoarthritis, results were lackluster and clinically insignificant.
The use of antimalarials was associated with a lower prevalence of congestive heart failure in a large Spanish cohort of patients with SLE.
For patients with rheumatoid arthritis, reduced levels of PA may impact disease activity, increase the likelihood of obesity, and may even lead to more frequent hospitalizations.
Analysis of self-reported wellness and health may provide insight into an overall subjective picture of wellbeing and health status. Mood, sleep quality, and sleep quantity were shown to impact these scores.
Plasma samples, collected from 21 patients with systemic juvenile idiopathic arthritis (sJIA), indicate 11 proteins that may help identify patients with active and inactive sJIA.
“Pregnancies in women with SLE are often complicated,” investigators stated. “Accordingly, it is crucial to optimize drug therapy to promote disease control and improve outcomes.”
Early diagnosis and prompt effective management are important for the best outcomes in rheumatoid arthritis. Test your knowledge of how to achieve this with this quiz.
Patients with systemic lupus erythematosus who were younger in age or were serologically active yet clinically quiescent were more likely to have disease flare during glucocorticoid cessation.
Investigators closely examine the differences between neuromuscular changes associated with normal aging and those associated with age-related disorders and how they affect individuals with knee osteoarthritis.
Among patients with psoriatic arthritis, a 36-item Short Form Health Survey was the best predictor of progression from oligoarticular to polyarticular arthritis.
Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending January 7, 2021.
While patients with rheumatoid arthritis on rituximab therapy have been reported to have insufficient serological responses to the COVID-19 vaccine, T cells, which protect against severe COVID-19, may be elevated after a third dose.
Results showed equivalent effectiveness in disease control between the novel drug, sirolimus, and the classic immunosuppressant, tacrolimus, for the treatment of systemic lupus erythematosus.
Patient-reported outcomes, in addition to physician assessment, suggest apremilast improves quality of life and symptoms of psoriatic arthritis within 6 months.
While patients with rheumatoid arthritis may benefit from either increasing or decreasing their dosage of tofacitinib, post-hoc analysis indicates that safety and efficacy of the medication is not impacted by these changes.
“As the therapeutic landscape for PsA evolves, evaluating the long-term safety of treatments is essential to understand benefit–risk profiles and inform patient care,” investigators explained.
An increased frequency of serious infections and antimicrobial prescriptions was seen in patients with rheumatoid arthritis currently being treated with a TNFi.
Treatment for rheumatoid arthritis has been associated with the development and worsening of some lung conditions. Test your knowledge with this quiz.
Review a hand-selected assortment of articles written for Rheumatology Network by top rheumatologists.
Catch up on Rheumatology Network's top highlights of the ACR 2021 Convergence.
