News

Although the primary outcomes of the US National Institutes of Health Women's Health Initiative trial suggested daily calcium plus vitamin D supplementation significantly reduced hip fracture in postmenopausal women, a follow-up investigation found no difference in hip fracture incidence between the study's supplement and placebo groups nearly 5 years after the intervention phase ended.

When does gout need treatment? A new set of staging criteria hopes to clarify the answer, and a separate report warns of the risks of unjustified treatment.

For antiphospholipid syndrome, some alternatives to vitamin K antagonists including rituximab and hydroxychloroquine may be suitable, says an international task force. Two clinical trials are recruiting to provide better information.

Ask your patients with psoriatic arthritis whether their disease impacts their work life. Like those in this study, they may say it takes quite a toll. What can you do to help?

The 56-year-old woman in this unique case study showed a rare, late involvement of the bones in sarcoidosis: herniated lumbar disks. Lung opacities turned up on CT, and a biopsy found noncaseating granuloma.

(ACR Pediatrics 2014) More links between the gut and arthritis: Children with spondyloarthritis have different enteric bacteria than healthy kids, adding to a growing body of evidence linking microbes to autoimmune disorders.

Little evidence exists to guide the management of treatment-resistant myositis. This brief guide describes the best available options for a challenging and heterogeneous condition.

Explanations for the "gender factor" in rheumatoid arthritis risk now include factors unique to the immune response among women, phenomena specific to pregnancy, and perhaps environmental factors including cosmetics.

Lofgren syndrome

The patient is plagued by problems: Severe headaches, nausea, vomiting, a rash, chest and abdominal pains, and by the time she reaches a rheumatologist, periorbital edema and photophobia. Can you guess the cause?

IL-17

Can drugs that target the shared interleukin 17/23 pathway improve on existing options for treatment of psoriatic arthritis? A brief overview discusses the options now in testing, and preliminary results.

A 58-year-old woman presented to clinic with concerns about this skin lesion on her upper chest. She reports it has been present for 1 year and is slowly enlarging. The lesion is otherwise asymptomatic and her past history is only significant for rheumatoid arthritis (RA), for which she takes methotrexate and etanercept.