
Afimetoran achieved SRI-4 response rates of 64.1% to 67.8% vs 34.4% with placebo in a phase 2 SLE trial.
Be aware that changes in geometry, bone mineral density, and micro-structure appear early in the disease course of axSpA.
Reference1. Neumann A, Haschka J, Kleyer A, et al. Cortical bone loss is an early feature of nonradiographic axial spondyloarthritis. Arthritis Res Ther. 2018;20:202. doi: 10.1186/s13075-018-1620-1.






