5 Questions About Idiopathic Inflammatory Myopathies

Recently, the European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) developed the first classification criteria for idiopathic inflammatory myopathies (IIMs).¹ Previous criteria for IIMs dated back from the 1970s and were based on expert opinion.

Test your knowledge of the latest IIM criteria with this 5-question quiz.

1. The International Myositis Classification Criteria Project (IMCCP) was established as a multidisciplinary collaboration of:

A. Rheumatologists and dermatologists

B. Pediatric rheumatologists and neurologists

C. Epidemiologists and biostatisticians

D. A and C

E. A, B, and C

Please click below for answer, discussion, and next question.

The correct answer is E. A, B, and C.

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2. Which of the following was not one of the three independent approaches used to develop the 93 classification criteria for idiopathic inflammatory myopathy (IIM)?

A. Sum-of-item approach

B. Freight-train approach

C. Classification-tree approach

D. Probability-score approach

Please click below for answer, discussion, and next question.

The correct answer is B. Freight-train approach.

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3. Which of these variables had the highest numbers of observations in IIM?

A. Electron microscopy examinations of muscle biopsies

B. Electromyography measurements

C. MRI measurements

D. Skin manifestations

Please click below for answer, discussion, and next question.

The correct answer is D. Skin manifestations.

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4. The minimal aggregate cutoff for probability that is necessary to classify a case as IIM is:

A. 80%

B. 65%

C. 55%

D. 40%

Please click below for answer, discussion, and next question.

The correct answer is C. 55%.

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5. Which of the following types of IIM represented too few cases to allow for subclassification?

A. Immune-mediated necrotizing myopathy

B. Dermatomyositis

C. Inclusion body myositis

D. Polymyositis

Please click below for answer and discussion.

The correct answer is A. Immune-mediated necrotizing myopathy.

References:

1. Bottai M, Tjärnlund A, Santoni G, et al. EULAR/ACR classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups: a methodology report.RMD Open. 2017;3:e000507. doi: 10.1136/rmdopen-2017-000507.

For More Information

New Criteria for Idiopathic Inflammatory Myopathies